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Article

Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation.

Science advances - 1 Jan 2020

Zhang Zheren, Du Chao, de Barsy Frédérique, Liem Michael, Liakopoulos Apostolos, van Wezel Gilles P, Choi Young H, Claessen Dennis, Rozen Daniel E

Abstract excerpt

One of the hallmark behaviors of social groups is division of labor, where different group members become specialized to carry out complementary tasks. By dividing labor, cooperative groups increase efficiency, thereby raising group fitness even if these behaviors reduce individual fitness. We find that antibiotic production in colonies of Streptomyces coelicolor is coordinated by a division of labor. We show...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31998842
DOI: 10.1126/sciadv.aay5781
PMCID: PMC6962034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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