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Genetic, clinic and histopathologic characterization of BRCA-associated hereditary breast and ovarian cancer in southwestern Finland.

Scientific reports - 25 Apr 2022

Pallonen Terhi Aino-Sofia, Lempiäinen Salla Maria Matleena, Joutsiniemi Titta Kristiina, Aaltonen Riitta Irmeli, Pohjola Pia Erika, Kankuri-Tammilehto Minna Kristiina

Abstract excerpt

We have analyzed the histopathological, clinical, and genetic characteristics in hereditary breast and ovarian cancer patients of counselled families from 1996 up to today in the southwestern Finland population. In this study we analyzed the incidence of different BRCA1 and BRCA2 pathogenic variants (PV). 1211 families were evaluated, and the families were classified as 38 BRCA1 families, 48 BRCA2 families, 689...

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Identifiers

PMID: 35469032
DOI: 10.1038/s41598-022-10519-y
PMCID: PMC9038668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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