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Article

Ashkenazi founder BRCA1/BRCA2 mutations in Slovak hereditary breast and/or ovarian cancer families.

Neoplasma - 1 Jan 2006

Cierniková S, Tomka M, Kovác M, Stevurková V, Zajac V

Abstract excerpt

Germline mutations in BRCA1 and BRCA2 have been predominantly associated with the breast and ovarian cancers. Two mutations in BRCA1 (185delAG and 5382insC) and one mutation in BRCA2 (6174delT) are common in Ashkenazi Jewish population. To determine the proportion of these founder mutations, we analyzed DNA samples of 120 Slovak hereditary breast and/or ovarian cancer (HBOC) suspected families. Two particular...

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Share to Founder Effect
Share to Genes, BRCA1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Ovarian Neoplasms

Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 16575464

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ashkenazi founder BRCA1/BRCA2 mutations in Slovak hereditary breast and/or ovarian cancer families.PMID 16575464Read ↗

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