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Article

Search for large genomic alterations of the BRCA1 gene in a Finnish population.

Cancer genetics and cytogenetics - 1 Nov 2005

Laurila Eeva, Syrjäkoski Kirsi, Holli Kaija, Kallioniemi Anne, Karhu Ritva

Abstract excerpt

Mutations in the BRCA1 and BRCA2 genes are known to predispose to breast cancer. In Finland, however, only 21% of all breast cancer families have mutations in these genes. Recent studies have shown that large genomic alterations of BRCA1 are common in many countries. Because such alterations will be missed in conventional mutation screening strategies, we decided to screen Finnish breast and ovarian cancer...

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Source

Identifiers

PMID: 16271956
DOI: 10.1016/j.cancergencyto.2005.05.014

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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