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Natural Bioactive Compounds Targeting Histone Deacetylases in Human Cancers: Recent Updates

15 Apr 2022

Abstract excerpt

Cancer is a complex pathology that causes a large number of deaths worldwide. Several risk factors are involved in tumor transformation, including epigenetic factors. These factors are a set of changes that do not affect the DNA sequence, while modifying the gene's expression. Histone modification is an essential mark in maintaining cellular memory and, therefore, loss of this mark can lead to tumor...

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PMID: 35458763
DOI: 10.3390/molecules27082568

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