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Article

Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates.

Journal of translational medicine - 1 Dec 2015

Mulu Andargachew, Maier Melanie, Liebert Uwe Gerd

Abstract excerpt

BACKGROUND: Although biochemical analysis of HIV-1 integrase enzyme suggested the use of integrase inhibitors (INIs) against HIV-1C, different viral subtypes may favor different mutational pathways potentially leading to varying levels of drug resistance. Thus, the aim of this study was to search for the occurrence and natural evolution of integrase polymorphisms and/or resistance mutations in HIV-1C Ethiopian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26626277
DOI: 10.1186/s12967-015-0734-3
PMCID: PMC4665939

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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