Article
Synergistic Effects of Weighted Genetic Risk Scores and Resistin and sST2 Levels on the Prognostication of Long-Term Outcomes in Patients with Coronary Artery Disease.
International journal of molecular sciences - 13 Apr 2022
Chou Hsin-Hua, Hsu Lung-An, Juang Jyh-Ming Jimmy, Chiang Fu-Tien, Teng Ming-Sheng, Wu Semon, Ko Yu-Lin
Abstract excerpt
Resistin and soluble suppression of tumorigenicity 2 (sST2) are useful predictors in patients with coronary artery disease (CAD). Their serum levels are significantly attributed to variations in RETN and IL1RL1 loci. We investigated candidate variants in the RETN locus for resistin levels and those in the IL1RL1 locus for sST2 levels and evaluated the prognostication of these two biomarkers and the corresponding...
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