Article
Combination of TRP channel dietary agonists induces energy expending and glucose utilizing phenotype in HFD-fed mice.
International journal of obesity (2005) - 1 Jan 2022
Kaur Jasleen, Kumar Vijay, Kumar Vibhu, Shafi Sadiah, Khare Pragyanshu, Mahajan Neha, Bhadada Sanjay K, Kondepudi Kanthi Kiran, Bhunia Rupam Kumar, Kuhad Anurag, Bishnoi Mahendra
Abstract excerpt
BACKGROUND: Bioactive dietary constituents activating Transient receptor potential (TRP) channels have emerged as promising candidates for the prevention of metabolic disorders. OBJECTIVE: The present study is an attempt to evaluate anti-obesity potential of a dietary TRP-based tri-agonist, combination of sub-effective doses of capsaicin (TRPV1 agonist), menthol (TRPM8 agonist), and cinnamaldehyde (TRPA1 agonist)...
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