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Article

Mutational Effect of Some Major COVID-19 Variants on Binding of the S Protein to ACE2.

Biomolecules - 13 Apr 2022

Li Zhendong, Zhang John Z H

Abstract excerpt

COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has many variants that accelerated the spread of the virus. In this study, we investigated the quantitative effect of some major mutants of the spike protein of SARS-CoV-2 binding to the human angiotensin-converting enzyme 2 (ACE2). These mutations are directly related to the Variant of Concern (VOC) including Alpha, Beta,...

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Identifiers

PMID: 35454161
DOI: 10.3390/biom12040572
PMCID: PMC9030943

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