Decisive gene strategy on osteoporosis: a comprehensive whole-literature-based approach for conclusive candidate gene targets.

doi:10.18632/aging.204026

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Article

Decisive gene strategy on osteoporosis: a comprehensive whole-literature-based approach for conclusive candidate gene targets.

Aging - 22 Apr 2022

Chen Yueh-Chun, Tsai Yu-Jui, Wang Chih-Chien, Ko Pi-Shao, Su Wen, Su Sui-Lung

Abstract excerpt

PURPOSE: Previous meta-analyses only examined the association between single gene polymorphisms and osteoporosis; there is no compilation of all gene loci that correlate with osteoporosis in the literature. In this study, we develop a new literature-based approach, a decisive gene strategy (DGS), to examine the sufficiency of the cumulative sample size for each gene locus and to assess whether a definite...

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PMID: 35452412
DOI: 10.18632/aging.204026
PMCID: PMC9085221

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