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Article

Ultrasonic Features and Molecular Subtype Predict Somatic Mutations in TP53 and PIK3CA Genes in Breast Cancer.

Academic radiology - 1 Dec 2022

Huang Yunxia, Qiang Yu, Jian Le, Jin Zhou, Lang Qian, Sheng Chen, Shichong Zhou, Cai Chang

Abstract excerpt

RATIONALE AND OBJECTIVES: To predict mutations in TP53 and PIK3CA genes in breast cancer using ultrasound (US) signatures and clinicopathology. MATERIALS AND METHODS: In this study, we developed and trained a model in 386 breast cancer patients to predict TP53 and PIK3CA mutations. The clinicopathological and US characteristics (including two-dimensional and color Doppler US) were investigated. Statistically...

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Identifiers

PMID: 35450798
DOI: 10.1016/j.acra.2022.02.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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