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Development and validation of ultrasound-based radiomics model to predict germline BRCA mutations in patients with breast cancer.

Cancer imaging : the official publication of the International Cancer Imaging Society - 29 Feb 2024

Deng Tingting, Liang Jianwen, Yan Cuiju, Ni Mengqian, Xiang Huiling, Li Chunyan, Ou Jinjing, Lin Qingguang, Liu Lixian, Tang Guoxue, Luo Rongzhen, An Xin, Gao Yi, Lin Xi

Abstract excerpt

BACKGROUND: Identifying breast cancer (BC) patients with germline breast cancer susceptibility gene (gBRCA) mutation is important. The current criteria for germline testing for BC remain controversial. This study aimed to develop a nomogram incorporating ultrasound radiomic features and clinicopathological factors to predict gBRCA mutations in patients with BC. MATERIALS AND METHODS: In this retrospective study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38424620
DOI: 10.1186/s40644-024-00676-w
PMCID: PMC10905812

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