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Article

Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach.

Clinical epigenetics - 19 Apr 2022

Neumann Alexander, Pingault Jean-Baptiste, Felix Janine F, Jaddoe Vincent W V, Tiemeier Henning, Cecil Charlotte, Walton Esther

Abstract excerpt

BACKGROUND: DNA methylation is an epigenetic mechanism involved in human development. Numerous epigenome-wide association studies (EWAS) have investigated the associations of DNA methylation at single CpG sites with childhood outcomes. However, the overall contribution of DNA methylation across the genome (R2Methylation) towards childhood phenotypes is unknown. An estimate of R2Methylation would provide context...

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Identifiers

PMID: 35440009
DOI: 10.1186/s13148-022-01268-w
PMCID: PMC9020033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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