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Epithelial Membrane Protein 1 Promotes Sensitivity to RSL3‐Induced Ferroptosis and Intensifies Gefitinib Resistance in Head and Neck Cancer

1 Jan 2022

Abstract excerpt

Epithelial membrane protein (EMP1), a member of the peripheral myelin protein (PMP22) family, is involved in the development of various human malignancies. However, the expression level of EMP1 and its functional role in head and neck squamous cell carcinoma (HNSCC) remain unclear to date. Ferroptosis, a newly characterized form of regulated cell death, plays an essential role in tumorigenesis. In this study, we...

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PMID: 35432717
DOI: 10.1155/2022/4750671

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