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Article

Interaction analysis between germline genetic variants and somatic mutations in head and neck cancer.

Oral oncology - 1 May 2022

Feng Guanying, Feng Hongjie, Qi Yibo, Wang Tianxiao, Ni Nan, Wu Jia, Yuan Hua

Abstract excerpt

OBJECTIVES: To evaluate interactions between germline genetic variants and somatic mutations in head and neck cancer (HNC). METHODS: The region enrichment analysis was performed to evaluate the enrichment of cancer driver genes (CDGs) in susceptibility regions. The pathway enrichment analysis was performed to identify common pathways of cancer driver genes and susceptibility genes. The association analysis was...

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PMID: 35428027
DOI: 10.1016/j.oraloncology.2022.105859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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