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Article

Unraveling most abundant mutational signatures in head and neck cancer.

International journal of cancer - 1 Jan 2021

Plath Michaela, Gass Johanna, Hlevnjak Mario, Li Qiaoli, Feng Bohai, Hostench Xavier Pastor, Bieg Matthias, Schroeder Lea, Holzinger Dana, Zapatka Marc, Freier Kolja, Weichert Wilko, Hess Jochen, Zaoui Karim

Abstract excerpt

Genomic alterations are a driving force in the multistep process of head and neck cancer (HNC) and result from the interaction of exogenous environmental exposures and endogenous cellular processes. Each of these processes leaves a characteristic pattern of mutations on the tumor genome providing the unique opportunity to decipher specific signatures of mutational processes operative during HNC pathogenesis and...

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PMID: 32930393
DOI: 10.1002/ijc.33297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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