Article
Cancer Relevance of Human Genes.
Journal of the National Cancer Institute - 11 Jul 2022
Qing Tao, Mohsen Hussein, Cannataro Vincent L, Marczyk Michal, Rozenblit Mariya, Foldi Julia, Murray Michael, Townsend Jeffrey P, Kluger Yuval, Gerstein Mark, Pusztai Lajos
Abstract excerpt
BACKGROUND: We hypothesize that genes that directly or indirectly interact with core cancer genes (CCGs) in a comprehensive gene-gene interaction network may have functional importance in cancer. METHODS: We categorized 12 767 human genes into CCGs (n = 468), 1 (n = 5467), 2 (n = 5573), 3 (n = 915), and more than 3 steps (n = 416) removed from the nearest CCG in the Search Tool for the Retrieval of Interacting...
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