Article
PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B‐cell lymphoma
1 Apr 2022
Abstract excerpt
Dear Editor, Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous disease,1 and the high-throughput sequencing has facilitated our understanding of genetic aberrations in DLBCL.2-4 The proviral integration site for Moloney murine leukemia virus 1 (PIM1), which encodes serine/threonine protein kinase, is identified as a target of aberrant somatic hypermutation in DLBCL5 and involved in tumorigenesis in...
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