Article
Genomic Mutation Landscape of Primary Breast Lymphoma: Next-Generation Sequencing Analysis.
Disease markers - 1 Jan 2022
Zhang Wenqi, Huang Chen, Liu Jingjing, Wu Lili, Zhang Huichao, Wu Xiaolin, Wang Lianjing, Li Weijing, Liu Wei, Liu Lihong
Abstract excerpt
Primary breast lymphoma (PBL) is a rare subtype of non-Hodgkin's lymphoma (NHL) with rapid progression and high risk of central nervous system metastasis. We have investigated 40 PBL patients retrospectively, and 16 of them were sequenced by a target panel of 112 genes related with lymphoma. Next-generation sequencing (NGS) identified 203 mutations spanning 35 genes and revealed seven potential protein-changing...
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