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Article

Head and neck squamous-cell cancer and its association with polymorphic enzymes of xenobiotic metabolism and repair.

Journal of toxicology and environmental health. Part A - 1 Jan 2008

Harth Volker, Schafer Martin, Abel Josef, Maintz Laura, Neuhaus Thomas, Besuden Mette, Primke Robert, Wilkesmann Anja, Thier Ricarda, Vetter Hans, Ko Yon-Dschun, Bruning Thomas, Bolt Hermann M, Ickstadt Katja

Abstract excerpt

Tobacco smoking, alcohol drinking, and occupational exposures to polycyclic aromatic hydrocarbons are the major proven risk factors for human head and neck squamous-cell cancer (HNSCC). Major research focus on gene-environment interactions concerning HNSCC has been on genes encoding enzymes of me...

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Source

Identifiers

PMID: 18569591
DOI: 10.1080/15287390801988160

Genes

ERCC2
GSTM1
GSTP1
GSTT1
NAT2
NQO1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18569591-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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