Evaluating breast cancer predisposition genes in women of African ancestry.

doi:10.1016/j.gim.2022.03.015

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Evaluating breast cancer predisposition genes in women of African ancestry.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jul 2022

Díaz-Zabala Héctor, Guo Xingyi, Ping Jie, Wen Wanqing, Shu Xiao-Ou, Long Jirong, Lipworth Loren, Li Bingshan, Fadden Mary Kay, Pal Tuya, Blot William J, Cai Qiuyin, Haiman Christopher A, Palmer Julie R, Sanderson Maureen, Zheng Wei

Abstract excerpt

PURPOSE: Studies conducted primarily among European ancestry women reported 12 breast cancer predisposition genes. However, etiologic roles of these genes in breast cancer among African ancestry women have been less well-investigated. METHODS: We conducted a case-control study in African American women, which included 1117 breast cancer cases and 2169 cancer-free controls, and a pooled analysis, which included...

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PMID: 35396981
DOI: 10.1016/j.gim.2022.03.015
PMCID: PMC9597482

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