Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Atypical Deep Penetrating Nevus With Mutations in Beta Catenin , BRAFV600E , and IDH1R132C in an 8-Year-Old Boy.

The American Journal of dermatopathology - 1 Aug 2022

Ireland Amanda M, Wood Benjamin A, Whitfield Joseph, Amanuel Benhur, Harvey Nathan T, Mesbah Ardakani Nima

Abstract excerpt

ABSTRACT: Deep penetrating nevus (DPN) is a pigmented melanocytic tumor which typically displays a wedge-shaped deep penetrating architecture. Some cases show a coexisting component resembling conventional melanocytic nevus. These morphological attributes are correlated with the acquisition of genomic alterations in the Wnt pathway on a background of underlying activating MAPK pathway mutations. Lesions with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nevus, Pigmented

Share to Skin Neoplasms

Source

Identifiers

PMID: 35385855
DOI: 10.1097/DAD.0000000000002198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Atypical Deep Penetrating Nevus With Mutations in Beta Catenin , BRAFV600E , and IDH1R132C in an 8-Year-Old Boy.PMID 35385855Read ↗

Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi.Semantic proximity Read ↗

Expanding the Molecular Landscape of Deep Penetrating Nevus-like Melanomas Beyond CTNNB1 and APC Mutations : A Clinicopathologic and Molecular Study of 14 Cases.Semantic proximity Read ↗

Deep penetrating nevus-like borderline tumors: A unique subset of ambiguous melanocytic tumors with malignant potential and normal cytogeneticsSemantic proximity Read ↗

Deep-penetrating-nevus-like melanoma arising in patients with familial adenomatous polyposis syndrome.Semantic proximity Read ↗

Combination of Congenital and Deep Penetrating Nevus by Acquisition of β-Catenin Activation.Semantic proximity Read ↗

Towards diagnostic criteria for malignant deep penetrating melanocytic tumors using single nucleotide polymorphism array and next-generation sequencing.Semantic proximity Read ↗

Combined WNT-activated deep-penetrating/plexiform melanocytoma: insights into clinicopathological and molecular characterization.Semantic proximity Read ↗

Molecular analysis of atypical deep penetrating nevus progressing to melanoma.Semantic proximity Read ↗

Histopathologic clues for the diagnosis of Wiesner nevus.Semantic proximity Read ↗

NRASQ61R-driven atypical melanocytic tumor with blue nevus-like morphology: A case report.Semantic proximity Read ↗

Mitotically Active Proliferative Nodule Arising in a Giant Congenital Melanocytic NevusSemantic proximity Read ↗

A novel phenotype with features of basal cell nevus syndrome and basaloid follicular hamartoma syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.