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Article

Deep-penetrating-nevus-like melanoma arising in patients with familial adenomatous polyposis syndrome.

Journal of cutaneous pathology - 1 Sept 2023

Russell-Goldman Eleanor, MacConaill Laura, Laga Alvaro C, Hanna John

Abstract excerpt

Deep penetrating nevi (DPN) are uncommon but distinctive melanocytic neoplasms that show an epithelioid to spindle cell morphology, prominent pigmentation with melanophages, and a plexiform growth pattern. Molecularly, most DPN are thought to be characterized by dual activation of the mitogen-activated protein kinase and the wingless-related integration site (Wnt) pathways, the latter being most commonly driven...

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PMID: 36688401
DOI: 10.1111/cup.14393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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