Article
Genetic impact of CDHR3 on the adult onset of asthma and COPD.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2020
Shigemasa Rie, Masuko Hironori, Hyodo Kentaro, Kitazawa Haruna, Kanazawa Jun, Yatagai Yohei, Iijima Hiroaki, Naito Takashi, Saito Takefumi, Hirota Tomomitsu, Tamari Mayumi, Sakamoto Tohru, Hizawa Nobuyuki
Abstract excerpt
BACKGROUND: Adult-onset asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous diseases caused by complex gene-environment interactions. A functional single nucleotide polymorphism of cadherin-related family member 3 (CDHR3), known as a receptor of rhinovirus-C, is associated with childhood-onset asthma especially in atopic individuals. OBJECTIVE: Here, we identified risk factors for...
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