Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zika virus infection accelerates Alzheimer’s disease phenotypes in brain organoids

2 Apr 2022

Abstract excerpt

Alzheimer's disease (AD) is one of the progressive neurodegenerative diseases characterized by β-amyloid (Aβ) production and Phosphorylated-Tau (p-Tau) protein in the cerebral cortex. The precise mechanisms of the cause, responsible for disease pathology and progression, are not well understood because there are multiple risk factors associated with the disease. Viral infection is one of the risk factors for AD,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Endoplasmic Reticulum Stress and Disease
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35368019
DOI: 10.1038/s41420-022-00958-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zika virus infection accelerates Alzheimer’s disease phenotypes in brain organoidsPMID 35368019Read ↗

Alzheimer's disease and COVID-19: Interactions, intrinsic linkages, and the role of immunoinflammatory responses in this process.Semantic proximity Read ↗

Viral Infection Induces Alzheimer’s Disease-Related Pathways and Senescence in iPSC-Derived Neuronal ModelsSemantic proximity Read ↗

Development of a high-throughput, quantitative platform using human cerebral organoids to study virus-induced neuroinflammation in Alzheimer’s diseaseSemantic proximity Read ↗

Cerebral organoids for modeling of HSV-1-induced-multiscale neuropathology associated with Alzheimer’s disease and phenotypic rescueSemantic proximity Read ↗

Alzheimer’s disease and infectious agents: a comprehensive review of pathogenic mechanisms and microRNA rolesSemantic proximity Read ↗

Cerebral Organoids for Modeling of HSV-1-Induced-Amyloid β Associated Neuropathology and Phenotypic Rescue.Semantic proximity Read ↗

Neurotropic virus infection and neurodegenerative diseases: Potential roles of autophagy pathwaySemantic proximity Read ↗

HSV-1 Infection Alters <i>MAPT</i> Splicing and Promotes Tau Pathology in Neural Models of Alzheimer’s DiseaseSemantic proximity Read ↗

Role of ANXA2, HSP90AA1 and PTK2B in synaptic homeostasis through microglial cells in the human entorhinal cortex in Alzheimer’s diseaseSemantic proximity Read ↗

HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's diseaseSemantic proximity Read ↗

From Viral Infections to Alzheimer’s Disease: Unveiling the Mechanistic Links Through Systems BioinformaticsSemantic proximity Read ↗

ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.