Article
Assignment of unimodal probability distribution models for quantitative morphological phenotyping.
BMC biology - 31 Mar 2022
Ghanegolmohammadi Farzan, Ohnuki Shinsuke, Ohya Yoshikazu
Abstract excerpt
BACKGROUND: Cell morphology is a complex and integrative readout, and therefore, an attractive measurement for assessing the effects of genetic and chemical perturbations to cells. Microscopic images provide rich information on cell morphology; therefore, subjective morphological features are frequently extracted from digital images. However, measured datasets are fundamentally noisy; thus, estimation of the true...
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