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Article

Functional Evaluation of Human Bioengineered Cardiac Tissue Using iPS Cells Derived from a Patient with Lamin Variant Dilated Cardiomyopathy.

International heart journal - 1 Jan 2022

Miura Koichiro, Matsuura Katsuhisa, Yamasaki Itoyama Yu, Sasaki Daisuke, Takada Takuma, Furutani Yoshiyuki, Hayama Emiko, Ito Masamichi, Nomura Seitaro, Morita Hiroyuki, Toyoda Masashi, Umezawa Akihiro, Onoue Kenji, Saito Yoshihiko, Aburatani Hiroyuki, Nakanishi Toshio, Hagiwara Nobuhisa, Komuro Issei, Shimizu Tatsuya

Abstract excerpt

Dilated cardiomyopathy (DCM) is caused by various gene variants and characterized by systolic dysfunction. Lamin variants have been reported to have a poor prognosis. Medical and device therapies are not sufficient to improve the prognosis of DCM with the lamin variants. Recently, induced pluripotent stem (iPS) cells have been used for research on genetic disorders. However, few studies have evaluated the...

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Identifiers

PMID: 35354754
DOI: 10.1536/ihj.21-790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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