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Article

Membrane Anchorage-Induced (MAGIC) Knockdown of Non-synonymous Point Mutations.

Chembiochem : a European journal of chemical biology - 3 Jun 2022

Ulaganathan Vijay Kumar

Abstract excerpt

The promise of personalized medicine for monogenic and complex polygenic diseases depends on the availability of strategies for targeted inhibition of disease-associated polymorphic protein variants. Loss of function variants, including non-synonymous single nucleotide variants (nsSNVs) and insertion/deletion producing a frameshift, account for the vast majority of disease-related genetic changes. Because it is...

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PMID: 35352864
DOI: 10.1002/cbic.202100637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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