Article
TP53 genetic polymorphisms, interactions with lifestyle factors and lung cancer risk: a case control study in a Chinese population.
BMC cancer - 27 Dec 2013
Li Yanli, Chang Shen-Chih, Niu Rungui, Liu Li, Crabtree-Ide Christina R, Zhao Baoxing, Shi Jianping, Han Xiaoyou, Li Jiawei, Su Jia, Cai Lin, Yu Shunzhang, Zhang Zuo-Feng, Mu Lina
Abstract excerpt
BACKGROUND: A pathway-based genotyping analysis suggested rs2078486 was a novel TP53 SNP, but very few studies replicate this association. TP53 rs1042522 is the most commonly studied SNP, but very few studies examined its potential interaction with environmental factors in relation to lung cancer risk. This study aims to examine associations between two TP53 single-nucleotide polymorphisms (SNPs) (rs2078486,...
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