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Recent advances in research on Mycobacterium tuberculosis virulence factors and their role in pathogenesis

29 Mar 2025

Abstract excerpt

Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB) in humans and animals. Mtb invades the host's lungs via airborne transmission, infecting macrophages and causing TB. In some cases, the infection can spread to other tissues and organs. Despite the availability of several drugs for TB treatment, the emergence of multidrug-resistant TB has led to high morbidity and mortality rates...

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PMID: 40175253
DOI: 10.1016/j.jmii.2025.03.017

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