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Contribution of Rs780094 and Rs1260326 Polymorphisms in GCKR Gene to Non-alcoholic Fatty Liver Disease: A Meta-Analysis Involving 26,552 Participants.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2021

Li Jiaying, Zhao Yuening, Zhang Hongxiang, Hua Wenxi, Jiao Wenzhi, Du Xuan, Rui Jingwen, Li Si, Teng Haiying, Shi Bimin, Yang Xiaoqin, Zhu Liyan

Abstract excerpt

BACKGROUND: Many published studies attempted to elucidate the implication of glucokinase regulator gene (GCKR) polymorphisms in the susceptibility to non-alcoholic fatty liver disease (NAFLD), but the results among them were still controversial. OBJECTIVE: This meta-analysis aims to precisely assess the relationship between the GCKR polymorphisms and the risk of NAFLD. METHODS: Systematic computerized searches in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33243135
DOI: 10.2174/1871530320999201126202706

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