Article
Replication analysis of genetic association of the NCAN-CILP2 region with plasma lipid levels and non-alcoholic fatty liver disease in Asian and Pacific ethnic groups.
Lipids in health and disease - 13 Jan 2016
Boonvisut Supichaya, Nakayama Kazuhiro, Makishima Saho, Watanabe Kazuhisa, Miyashita Hiroshi, Lkhagvasuren Munkhtulga, Kagawa Yasuo, Iwamoto Sadahiko
Abstract excerpt
BACKGROUND: The Neurocan-cartilage intermediate layer protein 2 (NCAN-CILP2) region forms a tight linkage disequilibrium (LD) block and is associated with plasma lipid levels and non-alcoholic fatty liver disease (NAFLD) in individuals of European descent but not in the Malay and Japanese ethnic groups. Recent genome-wide resequence studies identified a missense single-nucleotide polymorphism (SNP) (rs58542926)...
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