Roles of PLODs in Collagen Synthesis and Cancer Progression

Abstract excerpt

genes. Expression of PLODs is regulated by multiple cytokines, transcription factors and microRNAs. Dysregulation of PLODs promotes cancer progression and metastasis, suggesting that targeting PLODs is potential strategy for cancer treatment. Here, we summarize the recent progress in the investigation of function and regulation of PLODs in normal tissue development and disease progression, especially in cancer.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone and Dental Protein Studies
• Share to Cancer, Hypoxia, and Metabolism
• Share to Microbial metabolism and enzyme function