Article
KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma.
Frontiers in endocrinology - 1 Jan 2022
Lee Bo-Ching, Kang Victor Jing-Wei, Pan Chien-Ting, Huang Jia-Zheng, Lin Yu-Li, Chang Yi-Yao, Tsai Cheng-Hsuan, Chou Chia-Hung, Chen Zheng-Wei, Liao Che-Wei, Chiu Yu-Wei, Wu Vin-Cent, Hung Chi-Sheng, Chang Chin-Chen, Lin Yen-Hung
Abstract excerpt
Objective: Primary aldosteronism (PA) is the most common type of secondary hypertension, and it is associated with a higher rate of cardiovascular complications. KCNJ5 somatic mutations have recently been identified in aldosterone-producing adenoma (APA), however their influence on vascular remodeling and injury is still unclear. The aim of this study was to investigate the association between KCNJ5 somatic...
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