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Genetic Events Inhibiting Apoptosis in Diffuse Large B Cell Lymphoma

30 Apr 2021

Abstract excerpt

Diffuse large B cell lymphoma (DLBCL) is curable with chemoimmunotherapy in ~65% of patients. One of the hallmarks of the pathogenesis and resistance to therapy in DLBCL is inhibition of apoptosis, which allows malignant cells to survive and acquire further alterations. Inhibition of apoptosis can be the result of genetic events inhibiting the intrinsic or extrinsic apoptotic pathways, as well as their...

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PMID: 33946435
DOI: 10.3390/cancers13092167

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