Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole-exome sequencing in a Japanese multiplex family identifies new susceptibility genes for intracranial aneurysms.

PloS one - 1 Jan 2022

Maegawa Tatsuya, Akagawa Hiroyuki, Onda Hideaki, Kasuya Hidetoshi

Abstract excerpt

BACKGROUND: Intracranial aneurysms (IAs) cause subarachnoid hemorrhage, which has high rates of mortality and morbidity when ruptured. Recently, the role of rare variants in the genetic background of complex diseases has been increasingly recognized. The aim of this study was to identify rare variants for susceptibility to IA. METHODS: Whole-exome sequencing was performed on seven members of a Japanese pedigree...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exome Sequencing
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracranial Aneurysm

Share to Pedigree

Share to Subarachnoid Hemorrhage

Source

Open in PubMed Open full text

Identifiers

PMID: 35299232
DOI: 10.1371/journal.pone.0265359
PMCID: PMC8929693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-exome sequencing in a Japanese multiplex family identifies new susceptibility genes for intracranial aneurysms.PMID 35299232Read ↗

Genome-wide linkage analysis combined with genome sequencing in large families with intracranial aneurysms.Semantic proximity Read ↗

Whole Exome Sequencing in Patients with Phenotypically Associated Familial Intracranial Aneurysm.Semantic proximity Read ↗

RNF213 Is Associated with Intracranial Aneurysms in the French-Canadian Population.Semantic proximity Read ↗

Lessons learned from whole exome sequencing in multiplex families affected by a complex genetic disorder, intracranial aneurysm.Semantic proximity Read ↗

Identifying novel risk genes in intracranial aneurysm by integrating human proteomes and genetics.Semantic proximity Read ↗

Molecular genetics of human intracranial aneurysms.Semantic proximity Read ↗

Dissecting the Genetic Architecture of Intracranial Aneurysms.Semantic proximity Read ↗

Mapping a Mendelian form of intracranial aneurysm to 1p34.3-p36.13.Semantic proximity Read ↗

Genetics of Intracranial Aneurysms.Semantic proximity Read ↗

Multinational Genome-Wide Association Study and Functional Genomics Analysis Implicates Decreased SIRT3 Expression Underlying Intracranial Aneurysm Risk.Semantic proximity Read ↗

Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms.Semantic proximity Read ↗

Dissecting the Genetic Architecture of Intracranial AneurysmsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.