Whole Exome Sequencing in Patients with Phenotypically Associated Familial Intracranial Aneurysm.

Abstract excerpt

OBJECTIVE: Familial intracranial aneurysms (FIAs) are found in approximately 6%-20% of patients with intracranial aneurysms (IAs), suggesting that genetic predisposition likely plays a role in its pathogenesis. The aim of this study was to identify possible IA-associated variants using whole exome sequencing (WES) in selected Korean families with FIA. MATERIALS AND METHODS: Among the 26 families in our...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Exome Sequencing
• Share to Genetic Predisposition to Disease