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Tumor Mutational Burden From Circulating Tumor DNA Predicts Recurrence of Hepatocellular Carcinoma After Resection: An Emerging Biomarker for Surveillance.

Annals of surgery - 1 Sept 2024

Wehrle Chase J, Hong Hanna, Kamath Suneel, Schlegel Andrea, Fujiki Masato, Hashimoto Koji, Kwon David Choon Hyuck, Miller Charles, Walsh R Matthew, Aucejo Federico

Abstract excerpt

OBJECTIVE: Describe the utility of circulating tumor DNA in the postoperative surveillance of hepatocellular carcinoma (HCC). BACKGROUND: Current biomarkers for HCC like alpha-fetoprotein (AFP) are lacking. Circulating tumor DNA (ctDNA) has shown promise in colorectal and lung cancers, but its utility in HCC remains relatively unknown. METHODS: Patients with HCC undergoing curative-intent resection from November...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38860385
DOI: 10.1097/SLA.0000000000006386

Genes

AFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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