Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The interaction between smoking and bladder cancer genetic variants on urothelial cancer risk by disease aggressiveness.

Cancer medicine - 1 Aug 2022

Teleka Stanley, Jochems Sylvia H J, Jirström Karin, Stocks Tanja

Abstract excerpt

BACKGROUND: Smoking has shown interactions with bladder cancer (BC) genetic variants, especially N-acetyltransferase-2 (NAT2), a tobacco smoke metabolism gene, on BC risk. The interactions by disease aggressiveness are unknown. METHODS: We investigated the interaction between smoking and 18 single nucleotide polymorphisms (SNPs) for BC, individually and in a genetic risk score (GRS), on urothelial cancer (UC)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Transitional Cell

Share to Case-Control Studies

Share to Cytidine Deaminase

Share to Proteins

Share to Smoking

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 35285182
DOI: 10.1002/cam4.4654
PMCID: PMC9359879

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The interaction between smoking and bladder cancer genetic variants on urothelial cancer risk by disease aggressiveness.PMID 35285182Read ↗

Evaluating interactions of polygenic risk scores and NAT2 genotypes with tobacco smoking in bladder cancer risk.Semantic proximity Read ↗

Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis.Semantic proximity Read ↗

N-acetyltransferase 2 polymorphism is associated with bladder cancer risk: An updated meta-analysis based on 54 case-control studies.Semantic proximity Read ↗

Genome-wide interaction study of smoking and bladder cancer risk.Semantic proximity Read ↗

N-acetyltransferase 2 polymorphisms, tobacco smoking, and breast cancer risk in the breast and prostate cancer cohort consortium.Semantic proximity Read ↗

AKR1C2 genetic variants mediate tobacco carcinogens metabolism involving bladder cancer susceptibility.Semantic proximity Read ↗

Genetic susceptibility to bladder cancer with an emphasis on gene-gene and gene-environmental interactions.Semantic proximity Read ↗

Evidence for an intensity-dependent interaction of NAT2 acetylation genotype and cigarette smoking in the Spanish Bladder Cancer Study.Semantic proximity Read ↗

Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer.Semantic proximity Read ↗

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related riskSemantic proximity Read ↗

Slow N-acetylation as a possible contributor to bladder carcinogenesis.Semantic proximity Read ↗

Association Between N-acetyltransferase 2 Polymorphism and Bladder Cancer Risk: Results From Studies of the Past Decade and a Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.