Article
Cribriform-type adenocarcinoma of the colorectum: comprehensive molecular analyses of a distinctive histologic subtype of colorectal cancer.
Carcinogenesis - 27 Jun 2022
Yamada Shun, Osakabe Mitsumasa, Eizuka Makoto, Hashimoto Mai, Uesugi Noriyuki, Yanagawa Naoki, Otsuka Koki, Suzuki Hiromu, Matsumoto Takayuki, Sugai Tamotsu
Abstract excerpt
Colorectal adenocarcinoma (CRA) is characterized by marked heterogeneity and may be composed of an admixture of various histologic patterns, including well-formed gland and cribriform types. Although tumors displaying a prominent or predominant cribriform feature are frequently found in CRA, this type may contain specific histologic variants with a characteristic molecular alteration. We investigated the...
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