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Article

Current knowledge of small cell lung cancer transformation from non-small cell lung cancer.

Seminars in cancer biology - 1 Sept 2023

Giaccone Giuseppe, He Yongfeng

Abstract excerpt

Lung cancer is the leading cause of cancer related death, and is divided into two major histological subtypes, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Histological transformation from NSCLC to SCLC has been reported as a mechanism of treatment resistance in patients who received tyrosine kinase inhibitors (TKIs) targeting EGFR, ALK and ROS1 or immunotherapies. The transformed...

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Identifiers

PMID: 37244438
DOI: 10.1016/j.semcancer.2023.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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