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Article

Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin.

The Lancet. Oncology - 1 Apr 2015

Oser Matthew G, Niederst Matthew J, Sequist Lecia V, Engelman Jeffrey A

Abstract excerpt

Lung cancer is the most common cause of cancer deaths worldwide. The two broad histological subtypes of lung cancer are small-cell lung cancer (SCLC), which is the cause of 15% of cases, and non-small-cell lung cancer (NSCLC), which accounts for 85% of cases and includes adenocarcinoma, squamous-cell carcinoma, and large-cell carcinoma. Although NSCLC and SCLC are commonly thought to be different diseases owing...

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Source

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Identifiers

PMID: 25846096
DOI: 10.1016/S1470-2045(14)71180-5
PMCID: PMC4470698

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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