Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential role of hyperacetylated microtubules in innate immunity escape orchestrated by the EBV-encoded BHRF1 protein

11 Mar 2022

Abstract excerpt

Innate immunity constitutes the first line of defense against viruses, in which mitochondria play an important role in the induction of the interferon (IFN) response. BHRF1, a multifunctional viral protein expressed during Epstein-Barr virus reactivation, modulates mitochondrial dynamics and disrupts the IFN signaling pathway. Mitochondria are mobile organelles that move through the cytoplasm thanks to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cytomegalovirus and herpesvirus research
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35275978
DOI: 10.1371/journal.ppat.1010371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential role of hyperacetylated microtubules in innate immunity escape orchestrated by the EBV-encoded BHRF1 proteinPMID 35275978Read ↗

BHRF1, a BCL2 viral homolog, disturbs mitochondrial dynamics and stimulates mitophagy to dampen type I IFN inductionSemantic proximity Read ↗

Histone Deacetylase 8 Is Required for Centrosome Cohesion and Influenza A Virus EntrySemantic proximity Read ↗

BHRF1 Enhances EBV Mediated Nasopharyngeal Carcinoma Tumorigenesis through Modulating Mitophagy Associated with Mitochondrial Membrane Permeabilization TransitionSemantic proximity Read ↗

Viral Reprogramming of the Daxx Histone H3.3 Chaperone during Early Epstein-Barr Virus InfectionSemantic proximity Read ↗

Manipulation of Host Microtubule Networks by Viral Microtubule-Associated ProteinsSemantic proximity Read ↗

Microtubule Regulation and Function during Virus InfectionSemantic proximity Read ↗

Structural basis underlying viral hijacking of a histone chaperone complexSemantic proximity Read ↗

A phospho-regulated signal motif determines subcellular localization of α-TAT1 for dynamic microtubule acetylationSemantic proximity Read ↗

The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagySemantic proximity Read ↗

Endosomal removal and disposal of dysfunctional, immunostimulatory mitochondrial DNASemantic proximity Read ↗

Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagySemantic proximity Read ↗

Nuclear autophagy interactome unveils WSTF as a constitutive nuclear inhibitor of inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.