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Increased risk of polycystic ovary syndrome (PCOS) associated with CC genotype of miR-146a gene variation.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Sept 2018

Ebrahimi Seyed Omar, Reiisi Somayeh, Parchami Barjui Shahrbanou

Abstract excerpt

Polycystic ovary syndrome (PCOS) is an endocrinopathy in reproductive-age women believed to be affected by several genetics and environmental factors or both. Different miRNAs are one of such genetic factors that their associations with PCOS have been implicated. For instance, miR-146a that is well known for strongly regulating the immune response and inflammation was upregulated in serum plasma, follicular fluid...

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PMID: 29637801
DOI: 10.1080/09513590.2018.1460341

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