Article
Genetic Predisposition of Postoperative Adhesions Varies in Substrains of BALB/c Mice.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Jun 2022
Binda Maria Mercedes, Corona Roberta, Koninckx Philippe Robert
Abstract excerpt
Postoperative adhesions are a major clinical problem because of the associated infertility, chronic pain, bowel obstruction, and the associated costs. Variability in adhesion formation was suggested by clinical observations that apparently similar interventions can cause little to severe adhesions. This is supported by the presence of polymorphisms and genetic predisposition to develop adhesions in animal models...
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