Article
Selective inbreeding does not increase gut microbiota similarity in BALB/c mice.
Laboratory animals - 1 Oct 2012
Pang Wanyong, Stradiotto Damiano, Krych Lukasz, Karlskov-Mortensen Peter, Vogensen Finn Kvist, Nielsen Dennis Sandris, Fredholm Merete, Hansen Axel Kornerup
Abstract excerpt
Inflammatory diseases in mouse models are under strong impact from the gut microbiota. Therefore increased interindividual gut microbiota similarity may be seen as a way to reduce group sizes in mouse experiments. The composition of the gut microbiota is to a high extent defined by genetics, and it is known that selecting siblings as mothers even in inbred colonies may increase the gut microbiota similarity among...
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