Article
Rats develop more robust and persistent peritoneal adhesion phenotypes than mice: a multimodal comparative study.
Scientific reports - 14 May 2026
Li Junliang, Pu Zhenjun, Nian Hongyu, Ma Shengxu, Zhong Pengfei, Li Zhiyuan, Zhang Qiuning, Cai Hui
Abstract excerpt
This study aimed to compare the differences between rat and mouse models of peritoneal adhesions (PAs). The cecum-abdominal wall ischemic injury suture method was used to establish postoperative PA models in Sprague-Dawley rats and BALB/c mice. Adhesion progression was systematically evaluated via a multimodal system comprising imaging (micro-computed tomography [CT]), macroscopic scoring (Degree of Adhesion and...
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