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PSRC1 May Affect Coronary Artery Disease Risk by Altering CELSR2, PSRC1, and SORT1 Gene Expression and Circulating Granulin and Apolipoprotein B Protein Levels

18 Feb 2022

Abstract excerpt

Objective The aim of the study was to identify additional factors that contributed to coronary artery disease (CAD). Methods We conducted integrative analysis on publicly available data from genome-wide association studies and quantitative trait locus studies by employing Mendelian randomization methods to examine the associations of gene expression in liver cells and circulating protein levels with LDL-C and...

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PMID: 35252377
DOI: 10.3389/fcvm.2022.763015

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