Modulation of the unfolded protein response by the human hepatitis B virus

Abstract excerpt

During productive viral infection the host cell is confronted with synthesis of a vast amount of viral proteins which must be folded, quality controlled, assembled and secreted, perturbing the normal function of the endoplasmic reticulum (ER). To counteract the ER stress, cells activate specific signaling pathways, designated as the unfolded proteins response (UPR), which essentially increase their folding...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Endoplasmic Reticulum Stress and Disease
• Share to Hepatitis B Virus Studies
• Share to Hepatitis C virus research