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Article

SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma.

Life sciences - 1 May 2022

Li Yang, Feng Riyue, Yu Xiao, Li Lei, Liu Yuhao, Zhang Ruixiang, Chen Xiankai, Zhao Yahui, Liu Zhihua

Abstract excerpt

AIMS: Esophageal squamous cell carcinoma (ESCC) is one of the deadliest digestive tract cancer with poor prognosis. In our previous comprehensive genomics study, we identified that hotspot mutations in the solute carrier family 35 member E2 (SLC35E2) promoter region was significantly associated with worse prognosis in patients with ESCC. However, the biological function and molecular mechanism of SLC35E2 remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35247439
DOI: 10.1016/j.lfs.2022.120447

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